Abstract:

Vitreous substitutes play an important role in supporting vitreous chamber after vitro\|retinal surgery. The use of current vitreous substitutes has been limited due to their different issues. So the research for ideal vitreous substitutes is still a hot topic. Foldable capsular vitreous body is a new type of vitreous substitute which simulates vitreous cortex. It can be used for long\|term tamponade, with good physical, optical properties and biocompatibility. It can evenly support retina at all directions by filling with other vitreous substitutes, effectively reduce the complications and increase the remaining time of these substitutes. In addition, it can release different drugs as a drug delivery system. Foldable capsular vitreous body has good application prospects. But it also has the problem that it’s easy to cause complicated cataract which need further research and improvement. The observation of long\|term effect is also needed.  (Int Rev Ophthalmol, 2019, 43:  105-110)